2-Fluoro-4-methylpyridine-5-boronic acid

2-Fluoro-4-methylpyridine-5-boronic acid - Names and Identifiers

Name	2-Fluoro-4-methylpyridine-5-boronicacid
Synonyms	2-F -4-Me-5-pyridine boronic acid 3-Borono-6-fluoro-4-methylpyridine 2-Fluoro-4-methylpyridine-5-boronicacid 6-Fluoro-4-Methylpyridine-3-Boronic Acid 2-FLUORO-4-METHYLPYRIDINE-5-BORONIC ACID 6-Fluoro-4-methyl-3-pyridineboronic Acid 2-FLUORO-4-METHYL-5-PYRIDINEBORONIC ACID 2-Fluoro-4-methylpyridine-5-boronic acid 6-Fluoro-4-methylpyridine-3-boronic acid (6-FLUORO-4-METHYLPYRIDIN-3-YL)BORONIC ACID 6-fluoro-4-Methylpyridin-3-yl-3-ylboronic acid
CAS	1072944-18-3
InChI	InChI=1S/C6H7BFNO2/c1-4-2-6(8)9-3-5(4)7(10)11/h2-3,10-11H,1H3

2-Fluoro-4-methylpyridine-5-boronic acid - Physico-chemical Properties

Molecular Formula	C6H7BFNO2
Molar Mass	154.93
Density	1.28±0.1 g/cm3(Predicted)
Boling Point	331.6±52.0 °C(Predicted)
Flash Point	154.359 °C
pKa	7.05±0.58(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
MDL	MFCD08741406

2-Fluoro-4-methylpyridine-5-boronic acid - Introduction

2-Fluoro-4-methylpyridine-5-boronic acid, also known as 2-fluoro-4-methylpyridine-5-borate (FMPB), is an organoboron compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Colorless crystalline solid.
-Solubility: Soluble in many organic solvents, such as dimethyl sulfoxide, dimethylformamide, etc.
-Stability: relatively stable at room temperature.

Use:
-Catalyst: As a boron-containing catalyst, it is used in organic synthesis reactions, such as C- C bond formation, C- N bond formation, etc.
-Fluorescent probe: Due to its fluorescent properties, it can be used as a fluorescent probe agent for biological detection and imaging.

Preparation Method:
The preparation of-2-fluoro-4-methylpyridine-5-boronic acid can be completed by a two-step reaction.
-The first step is to condense 2-fluoro-4-methylpyridine with trimethylboronic acid to produce an intermediate.
-The second step is to react the intermediate with boronic acid or other boronic acid derivatives to obtain the product.

Safety Information:
-2-Fluoro-4-methylpyridine-5-boronic acid is a chemical and should follow appropriate safety procedures.
-Wear appropriate personal protective equipment such as gloves, goggles, and lab coats during use and handling.
-avoid contact with skin, eyes, respiratory tract, such as accidental contact, please immediately rinse with plenty of water.
-During storage and use, keep a well-ventilated environment to avoid fire and static electricity.
-When disposing of waste, it needs to be properly disposed of in accordance with local regulations.

Last Update：2024-04-09 21:04:16